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UniProt vs Protein Data Bank
Side-by-side comparison of UniProt (Dataset) and Protein Data Bank (Dataset).
Live Data← All Comparisons
80.9
Composite Score
UniProt
Dataset · UniProt Consortium (EMBL-EBI / SIB / PIR)
81.9
Composite Score
Protein Data Bank
Dataset · RCSB PDB / wwPDB Consortium
Overall Winner
Protein Data Bank
UniProt wins 1 of 6 categories · Protein Data Bank wins 3 of 6 categories
Score Comparison
UniProtvsProtein Data Bank
Composite
80.9:81.9
Adoption
93:95
Quality
97:97
Freshness
92:91
Citations
97:98
Engagement
0:0
Details
FieldUniProtProtein Data Bank
TypeDatasetDataset
ProviderUniProt Consortium (EMBL-EBI / SIB / PIR)RCSB PDB / wwPDB Consortium
Version2026.012026
Categoryscientificscientific
Pricingfreefree
LicenseCC BY 4.0CC0 1.0
DescriptionUniProt (Universal Protein Resource) is the world's comprehensive, freely accessible protein sequence and functional information database, maintained by a consortium of EMBL-EBI, SIB, and PIR. It contains over 250 million protein sequences in UniParc, with 570,000+ manually reviewed entries in SwissProt providing expert-curated functional annotations, and serves as the gold-standard training source for protein language models.The RCSB Protein Data Bank (PDB) is the single worldwide archive of experimentally determined 3D structures of proteins, nucleic acids, and complex assemblies, currently containing over 220,000 biological macromolecular structures determined by X-ray crystallography, NMR, and cryo-EM. It is the foundational structural dataset for computational biology and was used to train and validate AlphaFold2 and other structure-prediction models.
Capabilities
Only UniProt
protein-sequence-retrievalfunctional-annotationtaxonomy-search
Shared
None
Only Protein Data Bank
3d-structure-searchsequence-structure-mappingligand-binding-analysis
Integrations
Only UniProt
None
Shared
biopythonalphafold
Only Protein Data Bank
pymol
Tags
Only UniProt
sequencesfunctional-annotationbioinformatics
Shared
proteinsbiology
Only Protein Data Bank
structurescrystallographyalphafold
Use Cases
UniProt
- ▸protein language model training
- ▸drug target identification
- ▸functional genomics
Protein Data Bank
- ▸protein structure prediction training
- ▸drug design
- ▸structural biology research
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