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Protein Data Bank vs UniProt

Side-by-side comparison of Protein Data Bank (Dataset) and UniProt (Dataset).

81.9
Composite Score
Protein Data Bank
Dataset · RCSB PDB / wwPDB Consortium
80.9
Composite Score
UniProt
Dataset · UniProt Consortium (EMBL-EBI / SIB / PIR)
Overall Winner
Protein Data Bank
Protein Data Bank wins 3 of 6 categories · UniProt wins 1 of 6 categories

Score Comparison

Protein Data BankvsUniProt
Composite
81.9:80.9
Adoption
95:93
Quality
97:97
Freshness
91:92
Citations
98:97
Engagement
0:0

Details

FieldProtein Data BankUniProt
TypeDatasetDataset
ProviderRCSB PDB / wwPDB ConsortiumUniProt Consortium (EMBL-EBI / SIB / PIR)
Version20262026.01
Categoryscientificscientific
Pricingfreefree
LicenseCC0 1.0CC BY 4.0
DescriptionThe RCSB Protein Data Bank (PDB) is the single worldwide archive of experimentally determined 3D structures of proteins, nucleic acids, and complex assemblies, currently containing over 220,000 biological macromolecular structures determined by X-ray crystallography, NMR, and cryo-EM. It is the foundational structural dataset for computational biology and was used to train and validate AlphaFold2 and other structure-prediction models.UniProt (Universal Protein Resource) is the world's comprehensive, freely accessible protein sequence and functional information database, maintained by a consortium of EMBL-EBI, SIB, and PIR. It contains over 250 million protein sequences in UniParc, with 570,000+ manually reviewed entries in SwissProt providing expert-curated functional annotations, and serves as the gold-standard training source for protein language models.

Capabilities

Only Protein Data Bank

3d-structure-searchsequence-structure-mappingligand-binding-analysis

Shared

None

Only UniProt

protein-sequence-retrievalfunctional-annotationtaxonomy-search

Integrations

Only Protein Data Bank

pymol

Shared

biopythonalphafold

Only UniProt

None

Tags

Only Protein Data Bank

structurescrystallographyalphafold

Shared

proteinsbiology

Only UniProt

sequencesfunctional-annotationbioinformatics

Use Cases

Protein Data Bank

  • protein structure prediction training
  • drug design
  • structural biology research

UniProt

  • protein language model training
  • drug target identification
  • functional genomics
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